The Anti-Collagen, Type IV antibody (monoclonal) from MyBioSource.com is a Mouse Monoclonal antibody to Arresten, BRU, COL4A1, HANAC, and POREN1. This antibody recognizes Human antigen. The Anti-Collagen, Type IV antibody (monoclonal) has been validated for the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Description: Mouse IgG monoclonal antibody for Collagen, Type IV, collagen, type IV, alpha-1, collagen, type IV, alpha 3 (Goodpasture antigen), collagen,type IV, alpha 4, collagen, type IV, alpha 5, collagen, type IV, alpha 6 (COL4A1, COL4A3, COL4A4, COL4A5, COL4A6) detection. Tested with IHC-P, IHC-F in Human. No cross reactivity with other proteins. Uniprot ID: P02462
Background: Collagen IV is comprised of a third chain(alpha-3) together with the 2 classical ones, alpha-1 and alpha-2. COL4A3 gene is localized to 2q36-q37 by analysis of somatic cell hybrids and by in situ hybridization. The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria